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Researchers map genetic changes in glioblastoma as it progresses, test potential treatment strategy
In a pair of preclinical studies published in the journal Neuro-Oncology, UNC Lineberger's C. Ryan Miller, MD, PhD, and the Phoenix-based Translational Genomics Research Institute report on the genetic evolution of glioblastoma as it progresses in severity and a potential strategy to treat this often fast-growing brain cancer type.
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UNC Lineberger researchers to study prostate cancer treatment side effects, survival outcomes
The use of robot-assisted surgery and modern radiation techniques have been rapidly adopted as treatments for prostate cancer, but a UNC Lineberger Comprehensive Cancer Center researcher is asking what the newer technologies will mean in terms of side effects and outcomes for patients in the long-term.
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Insurance, distance to care can be barriers to breast reconstruction
Researchers say breast reconstruction can help with self-esteem, sexuality and body image after cancer treatment. But a UNC Lineberger study led by Michelle Roughton, MD, has found that the type of insurance a woman has as well as distance to a plastic surgeon's office can be barriers to the procedure.
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New UNC Lineberger faculty recruited to launch T-cell cancer therapy trials
Two new faculty members have joined the UNC Lineberger Comprehensive Cancer Center to help launch groundbreaking immunotherapy clinical trials that will test an experimental treatment in which patients’ own immune cells are genetically engineered to fight their cancer.
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UNC Lineberger launches innovative cellular immunotherapy program
UNC Lineberger, with its U.S. FDA-approved Good Manufacturing Practices, or “clean,” facility, is one of only a select academic centers in the United States with the capability to genetically modify patient immune cells for clinical use. This makes it possible for people who live in the Southeastern U.S. to stay closer to home to undergo cellular immunotherapy treatment.
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UNC Lineberger awards more than $1.5 million for cancer research
Twelve cancer researchers have won awards from the spring cycle of the UNC Lineberger Comprehensive Cancer Center’s Developmental Grants program for basic science, clinical/translational and population-based cancer research.
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Researchers explore roots of breast cancer disparities at symposium
A symposium co-sponsored by the UNC Lineberger Comprehensive Cancer Center brought leading breast cancer researchers together Friday to share findings about the genetic and environmental factors driving disparities in the disease’s incidence and mortality.
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Racial gaps persist in how breast cancer survivors function, feel during treatment and after
A UNC Lineberger study published in the journal Breast Cancer Research and Treatment drew upon surveys that assessed health-related quality of life issues for women aged 20 to 74 years who lived in North Carolina and had breast cancer. The analysis was part of the third phase of the Carolina Breast Cancer Study.
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Images of health risks make indoor tanning messages more effective
UNC Lineberger's Seth Noar, PhD, and colleagues report in a new study that anti-tanning bed messages with images showing longer-term health effects, such as skin cancer or wrinkles, produced greater negative emotional reactions and higher ratings of effectiveness in a survey of female college students than text-only messages.
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Researchers unlock mechanism of drug resistance in aggressive breast cancer
In the journal Cancer Discovery, UNC Lineberger's Gary Johnson, PhD, and colleagues published findings on how triple negative breast cancer cells are able to bypass treatment with trametinib, an FDA-approved kinase inhibitor. They also demonstrated in a laboratory model a potential treatment approach that could prevent the onset of resistance.
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