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Jill Dowen
Jill Dowen, PhD, is a UNC Lineberger Comprehensive Cancer Center member and Assistant Professor in the Biochemistry and Biophysics Department and the Biology Department at UNC-Chapel Hill. Dr. Dowen's lab is investigating the function of DNA loops involving genes and their regulatory elements.
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Genomic analysis paves way for personalized treatment of invasive lobular carcinoma
UNC Lineberger Comprehensive Cancer Center researchers helped lead an effort by The Cancer Genome Atlas Network of researchers to map the genetic drivers of invasive lobular carcinoma, the second most commonly diagnosed invasive form of breast cancer. They found that this cancer type may be at least three different diseases that differ in their microenvironmental features and outcomes.
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UNC Lineberger to partner in $12 million effort to find treatments for genetically-linked cancers
UNC Lineberger Comprehensive Cancer Center researchers and eight other leading cancer research institutions have won a five-year, $12 million grant to try to find treatments for a group of cancers linked to mutations in the NF1 gene.
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Researchers from UNC Lineberger, Norway launch cancer genetics collaboration
Researchers from Norway visited UNC Lineberger Comprehensive Cancer Center to learn firsthand about UNCseq, a clinical trial launched in 2011 at the N.C. Cancer Hospital. In the trial, researchers use a profile of the genetic and molecular alterations in patients' tumors to try to identify targeted treatments for them.
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Pancreatic cancer subtypes discovered in largest gene expression analysis of the disease to-date
A UNC Lineberger-led study, published today in Nature Genetics, paves the way for potential personalized medicine approaches for the deadly cancer type.
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Precision medicine at UNC: Looking for cancer-driving gene mutations across cancers
UNC Lineberger will be enrolling patients into a new, national clinical trial, known as NCI-MATCH, that will group patients based on the genetics of their tumors as opposed to where their cancer is located. The new initiative will test more than 20 drugs or drug combinations targeting specific genetic mutations.
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UNC Lineberger breast cancer researcher wins ASCO foundation grant
Katherine Reeder-Hayes, MD, MBA, Msc, a UNC Lineberger member and a clinical assistant professor in the University of North Carolina School of Medicine, won a Career Development Award from the Conquer Cancer Foundation of the American Society of Clinical Oncology. She was one of 11 clinical investigators chosen to receive the three-year award, which goes to researcher-physicians to help them build independent clinical research programs.
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