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Device hits pancreatic tumors hard with toxic four-drug cocktail, sparing the body
A new implantable device delivers first-line treatment for pancreatic cancer directly to tumors, bypassing bloodstream and limiting widespread side effects. A team of researchers from the University of North Carolina including Drs. Jen Jen Yeh and Joseph DeSimone, has shown in preclinical research that the device can deliver a particularly toxic dose of drugs directly to pancreatic tumors to stunt their growth or, in some cases, shrink them. This approach would also spare the patient toxic side effects.
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Preclinical study finds no benefit for diabetes drug in pancreatic cancer
UNC Lineberger researchers found in a study published in PLOS ONE that the diabetes drug metformin failed to show any benefit against pancreatic cancer, despite excitement about the drug for potential anti-cancer benefits. They believe the study shows the importance of testing new therapies in preclinical animal models that incorporate actual tumor tissue to better predict patient response.
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Trainee Kirsten Bryant Awarded AACR Pathway to Leadership Grant
The Pancreatic Cancer Action Network-AACR Pathway to Leadership Grant represents a joint effort to ensure the future leadership of pancreatic cancer research by supporting outstanding early career investigators beginning in their postdoctoral research positions and continuing through their successful transition to independence.
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Potential pancreatic cancer treatment could increase life expectancy
Device that drives drugs into solid tumors that are poorly vascularized opens the possibility of life-saving surgeries in cancer patients.
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UNC researchers trade lab coats for running shoes
Kirsten Bryant, PhD, was recently recognized by the Pancreatic Cancer Action Network for her dual role in the fight against pancreatic cancer.
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UNC Lineberger teams to participate in Pancreatic Cancer Purple Stride 5K
UNC Lineberger will be well represented at the 2014 Pancreatic Cancer Purple Stride 5K. The event, organized by the Pancreatic Cancer Action Network, helps raise awareness and research funds for pancreatic cancer.
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Channing Der presents lecture at Pancreatic Cancer Action Network
Der highlighted recent research findings that have stimulated new experimental directions for improve therapies for pancreatic cancer.
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