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Eleni Tzima

Eleni Tzima

  • Ph.D.
  • Cancer Cell Biology

  • Cell and Molecular Physiology
  • UNC-Chapel Hill
  • etzima@med.unc.edu
  • 843-9455
  • 6341-C MBRB

Area of Interest

The endothelium, which lines the entire circulatory system, acts as a dynamic interface between the vascular compartment and the extravascular space. The vascular endothelium regulates hemostasis, cellular proliferation, inflammatory and immune mechanisms. The endothelium is also critical to both intravasation and extravasation of tumor cells. First, tumors must be vascularized via angiogenesis by ECs to provide the supply of nutrients for the growth of the tumor mass and the route of intravasation. Second, adhesion to the vascular endothelium is essential for exit of tumor cells from the blood into secondary sites. Our work is focused on two areas: 1) design of inhibitors of angiogenesis; and 2) mechanisms of metastasis.

Awards and Honors

1997 European Research Conference Travel Grant
1998 National Heart Research Fund Short-term Fellowship
1998 British Society for Haemostasis and Thrombosis Fellowship
1998 American Society for Cell Biology Predoctoral Award Travel Grant
1996-99 British Heart Foundation Doctoral Fellowship
2002 Dr. Frederick Valergakis Research Grant
2003-04 American Heart Association Western States Postdoctoral Affiliate
2004 National Heart, Lung and Blood Institute, National Institutes of Health, Trainee Award
2004 Wellcome Trust Career Development Award
2004 Medical Research Council Career Development Award
2004 Royal Society University Research Fellowship
2004 British Heart Foundation Lectureship
2006 North American Vascular Biology Organization Junior Investigator Award Finalist
2006 Scientist Development Grant, American Heart Association, USA
2006 Searle Scholar Award Nominee
2007 R.J. Reynolds Fund Award
2007 Ellison Medical Foundation New Scholar Award in Aging