William K. Funkhouser
- MD, PhD
- Clinical Research
- Thoracic Oncology Program
- Urologic Oncology Program
- Professor, Pathology and Laboratory Medicine
- UNC-Chapel Hill
- 304 Brinkhous-Bullitt Building, CB# 7525, UNC, Chapel Hill, NC 27599-7525
Area of Interest
My service responsibilities include surgical pathology (pulmonary, cardiac, pulmonary/cardiac transplantation, ENT, GU, endocrine, bone/ST), and molecular pathology.
I am interested in developing rapid methods of obtaining genotypic and phenotypic data from frozen and formalin-fixed tissue, as well as the subsequent testing of these data as independent predictors of clinical outcome. We are currently interested in 1) mismatch repair defects in human carcinomas, 2) correlation of mRNA and protein expression for known prognostic loci in non-small cell lung carcinoma, 3) generation of stable reusable solid phase cDNA libraries, and 4) molecular definition of neoplastic clonotype.