UNC surgeon-scientist Dr. Nancy DeMore says, “As a physician, I’m acutely aware of how much more we need to learn about breast cancer and how urgently we need better therapies. It really gives me hope to be in the lab and to know that I’m working towards something that may make things better for patients.”
Kurt Ribisl, PhD, is co-author of the article “Internet Alcohol Sales to Minors” published online ahead of print in the May 2012 issue of the Archives of Pediatrics & Adolescent Medicine.
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, is quoted in an article discussing the fetal genome and the possibility of clinic procedures being introduced in the next couple of years.
Deborah Mayer, PhD, RN, AOCN, FAAN, associate professor in the UNC School of Nursing, has been appointed to a three-year term on the Cancer Survivorship Committee of the American Society of Clinical Oncology.
Victoria Bae-Jump, MD, PhD, has received a two-year $200,000 grant from the Department of Defense, to study “Preclinical and Clinical Investigations of the Impact of Obesity on Ovarian Cancer Pathogenesis.”
WCHL named Jennifer Bowman a Hometown Hero for June 11, 2012. Each weekday the station selects a Hometown Hero who goes “over and above the call of duty,” exemplifying excellent service and dedication to others in the community.
CHAPEL HILL, N.C. – A recent clinical trial testing a combination therapy for basal-like (also known as triple-negative) breast cancer demonstrates that a combination of two drugs with promising preclinical results is not as effective as researchers had hoped.
Votes, not baskets, will propel Cornucopia House to the Final Four in a national competition for a $25K mobile technology grant from AtlanticBT.
A gene known to be mutated in many different cancers, but thought to be relatively unimportant in melanoma, may be a key indicator of how the disease will respond to radiation therapy and whether it will spread.
Chapel Hill, NC – Why do some cancers spread rapidly to other organs and others don’t metastasize? A team of UNC researchers led by Norman Sharpless, MD, have identified a key genetic switch that determines whether melanoma, a lethal skin cancer, spreads by metastasis.
Lisa Carey, MD, authored an editorial, titled “Neoadjuvant Trials of Human Epidermal Growth Factor Receptor 2 Targeting: How Many Drugs Do We Need?”
Carey Anders, MD, and William Kim, MD, were awarded grants from the Damon Runyon Cancer Research Foundation.
Newly-Formed Collaboration to Focus on Vaccines and Inhaled Therapeutics
Following a blood stem cell transplant, survivors can face serious economic challenges that may negatively affect their quality of life.
Chapel Hill, NC – Debbie C. Dibbert, Director of External Affairs at UNC Lineberger Comprehensive Cancer Center, has been elected president of the National Association of Cancer Center Development Officers (NACCDO). She will serve a two-year term.
Presents invited lecture at Harvard Medical School
Genetic Marker in the Vitamin D Receptor Gene Associated With Increased Overall Survival for Pancreatic Cancer Patients
By Jeremy Moore
A new analysis done by University of North Carolina at Chapel Hill researchers has found that physical activity - either mild or intense and before or after menopause - may reduce breast cancer risk, but substantial weight gain may negate these benefits.
Todd Auman, PhD, has been appointed director of UNC Lineberger Comprehensive Cancer Center’s Tissue Procurement Facility.
New JAMA study shows stepped-care intervention results in weight loss at lower cost, UNC's Deborah Tate co-author
A customized weight loss program may cost less to implement – despite having similar results – than a traditional weight loss program, according to a study published in the June 27 issue of The Journal of the American Medical Association (JAMA).
Parking difficulties inspired Barbara Riff to take motorcycle lessons with her son. Now she commutes to work via motorcycle and frequently takes motorcycle trips for fun.
CHAPEL HILL, NC – Sometimes, technology progresses faster than our ability to take advantage of it.
Bruce Ham heard about the “Support Program for Single Fathers” from a friend. “I attended the first meeting. The guys in the group were going through exactly what I was going through and they were a similar age, they had all lost their wives to cancer, they all had kids in the house, so we had a lot in common. That’s what made it appealing to me.”
What are cancer rumors and why do people share them?
UNC Lineberger honored five clinical fellows for their research accomplishments and clinical excellence.
A diet based on American junk food could lead to more obesity-induced inflammation than a diet high in animal fat, according to a new study by researchers at the University of North Carolina at Chapel Hill.
Increased fatty acid synthesis is a metabolic signature of non-Hodgkin lymphoma
When scientists and advocates join forces, good things can happen. Dr. Channing Der, Sarah Graham Kenan Professor of Pharmacology and UNC Lineberger faculty member, and Lori Matteson, a Raleigh pancreatic cancer survivor and advocate, joined over 600 other pancreatic cancer advocates and family members on a visit to Washington, DC.
Karyn Stitzenberg, MD, MPH, has been appointed to a four-year term on the North Carolina Advisory Committee on Cancer Coordination and Control.
CHAPEL HILL, NC – Scientists at the University of North Carolina School of Medicine have used injections of antibodies to rapidly reverse the onset of Type I diabetes in mice genetically bred to develop the disease. Moreover, just two injections maintained disease remission indefinitely without harming the immune system.
Researchers at UNC have proposed a novel interpretation of an old biomarker which, if validated, could fundamentally transform the management of head and neck cancer.
John Strader, PA-C with the hematologic malignancies program, was honored as the 2012 Man of the Year by the Leukemia & Lymphoma Society, North Carolina chapter, raising over $30,000 for the organization.
Keith Amos, MD, assistant professor of surgery at UNC-Chapel Hill, is quoted in an ABC News feature discussing a new study about partial breast removal surgery to treat cancer.
The University of North Carolina at Chapel Hill’s Frank Hawkins Kenan Institute of Private Enterprise has appointed Joseph M. DeSimone as its new director.
Chapel Hill - From the air, the twists and turns of rivers can easily be seen. In the body, however, tracing the twists and turns of blood vessels is difficult, but important. Vessel “bendiness” can indicate the presence and progression of cancer.
Overall, eleven specialties at UNC Hospitals were recognized as nationally ranked or high performing by U.S. News & World Report in its annual "America's Best Hospitals" issue.
Rachel Roper, PhD, Associate Professor of Microbiology & Immunology at East Carolina’s Brody School of Medicine has been granted a patent for her discovery of a poxvirus gene that, when deleted, significantly weakens the vaccine virus while simultaneously increasing immune responses to it.
RALEIGH, NC – Crown Imports announced today that the highly successful “Corona Cares” charitable donation program in North Carolina will kick off on August 1 to benefit patient and family support programs at the N.C. Cancer Hospital. Over the past two years, “Corona Cares” has provided more than $210,000 for these programs.
Dittmer selected to serve as chair of AIDS-Associated Opportunistic Infections and Cancer Study Section
Dirk Dittmer, PhD, professor of microbiology and immunology, has been selected to serve as chair of the AIDS-Associated Opportunistic Infections and Cancer Study Section, for the Center for Scientific Review, a program of the National Institutes of Health.
Ana McCrory of the Tissue Culture Facility will be making a special trip to London in July. She, her husband, Doug, their son, Lucas, and other family members are traveling to cheer on her son, Nick, who is a member of the 11-member US diving team for the 2012 Summer Olympics.
The Cancer Genome Atlas generates genomic data for colon and rectal cancers that point to potential targets for treatment.
Three UNC graduate students were awarded International Predoctoral Fellowships by the Howard Hughes Medical Institute. Onur Dagliyan, Alakananda Das, and Mira Pronobis each received a $43,000 fellowship.
Vaccines against human papillomavirus (HPV) are now recommended by the Centers for Disease Control and Prevention for both teenage boys and girls. The vaccine protects against the two most common types of the virus that cause cervical cancer: HPV 16 and 18. Is there a chance that the increased number of people vaccinated might result in an increase of other types of HPV that cause cancer?
Life is full of choices, and even cells come to a fork in the road. They have to decide what to do about damage to their DNA: repair the damage, force the damaged cell to die, or allow the damage to transform the cell to a tumor cell.
Three UNC Lineberger researchers are collaborating on a project recently awarded more than $3.3 million over five years from the National Institutes of Health’s National Heart, Lung, and Blood Institute.
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, is quoted in an article on NPR's website discussing a recent request by a genetic test maker for the Food and Drug Administration to approve its personalized DNA test.
Joseph DeSimone, PhD, Chancellor's Eminent Professor of Chemistry, gave an interview to EarthSky regarding his green inventions, his current work and the future of science.
Nick McCrory, the son of Ana and Doug McCrory, won a bronze medal in the Olympic men’s 10-meter synchronized diving competition with partner David Boudia. Nick’s mother, Ana, works in the UNC Lineberger Tissue Culture Facility.
Chapel Hill, NC – Carmina G. Valle, MPH, is the recipient of the first Marci Kramish Campbell Dissertation Award, a competitive $5,000 award to recognize excellence in dissertation research focused on cancer and the population sciences.
A UNC-led team of scientists describes the function of a previously uncharacterized protein that dramatically influences inflammation.
Hy Muss, MD, and Debra Bynum, MD, co-authored an editorial in the July 20, 2012 issue of the Journal of Clinical Oncology.
A Randolph County woman with leukemia receives stem cells from her youngest brother in hopes of restoring her health and returning to work as a baker.
Chapel Hill, NC – Leukemia and lymphoma patients who receive life-saving stem cell or bone marrow transplants often experience chronic side effects that significantly decrease quality of life, can last a lifetime, and ultimately affect their long-term survival.
The V Foundation for Cancer Research, one of the nation’s leading cancer research foundations, has awarded a $600,000 grant to a UNC Lineberger team.
Chapel Hill, NC – A laboratory study led by UNC medical oncologist Stergios Moschos, MD, demonstrates how a new targeted drug, Elesclomol, blocks oxidative phosphorylation, which appears to play essential role in melanoma that has not been well-understood.
UNC Head Basketball Coach Roy Williams and UNC Lineberger physician-scientist Kim Rathmell, MD, PhD, were featured speakers at the American Cancer Society’s Cancer Action Network breakfast, held August 24th in Research Triangle Park.
Kayaking and rock climbing aren’t usual clinical activities for UNC Lineberger medical oncologist Dr. Juneko Grilley-Olson and nurse practitioner Elizabeth Sherwood, but they were during the time that each volunteered for a First Descents camp week for young adult cancer survivors.
UNC-Chapel Hill rose to ninth from 16th among leading private and public research universities for the level of federal funding ($545.99 million) devoted to research and development in all fields during fiscal 2010.
GeneCentric now has two separate exclusive licenses to diagnostic technologies from the University of North Carolina at Chapel Hill. The company was co-founded in 2011 by UNC Lineberger researchers Drs. Charles Perou and Neil Hayes, who discovered molecular signatures critical in distinguishing clinically relevant subtypes of lung cancer.
The WTX gene is mutated in approximately 30 percent of Wilms tumors, a pediatric kidney cancer. Like many genes, WTX is part of a family. In this case, WTX has two related siblings, FAM123A and FAM123C.
Wanda Wooten talks with NBC 17 about the day she was diagnosed with ovarian cancer and her treatment and offers encouragement to other women facing ovarian cancer.
UNC scientists were co-principal investigators and collaborators for projects described in the September 6, 2012 special issue of the journal Nature describing the ENCODE (Encyclopedia of DNA Elements) Project.
Changes in DNA that are important to the initiation and progression of lung cancer also identified by NIH-supported researchers
Dr. Angelique Whitehurst, assistant professor of pharmacology, was awarded a 2011 Innovative Research Grant from Stand Up to Cancer, the scientific partner of the American Association of Cancer Research.
Chapel Hill, NC – A mysterious form of cell death, coded in proteins and enzymes, led to a discovery by UNC researchers uncovering a prime suspect for new cancer drug development.
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, is quoted in NPR's second story in its "$1,000 Genome" series, which aired today.
UNC Lineberger faculty co-author review article on adjuvant chemotherapy in women 70 years of age and older
Preclinical testing a necessary step in drug development
Chapel Hill, NC – The cost of sequencing the entire human genome, or exome – the regions of the genome that are translated into proteins that affect cell behavior – has decreased significantly, to the point where the cost of looking at the majority of a patient’s genomic data may be less expensive than undertaking one or two targeted genetic tests.
Chapel Hill, NC –Researchers have long known that individual diseases are associated with genes in specific locations of the genome.
Carey named Division Chief of Hematology-Oncology and Physician-in-Chief of the N.C. Cancer Hospital
Chapel Hill - Lisa A. Carey, MD, has been appointed Chief of the Division of Hematology and Oncology at the University of North Carolina School of Medicine and Physician-in-Chief of the N.C. Cancer Hospital.
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, provided his perspective on a HuffPost Live broadcast that aired on September 24, 2012.
Team identifies genetic causes and similarity to ovarian cancer
Blossom Damania, PhD, and Dirk Dittmer, PhD, both have lived all over the world, where they saw firsthand the global burden of cancer. Both are professors of microbiology and immunology in the UNC school of Medicine and members of UNC Lineberger.
Chapel Hill, NC – More than 50 Chapel Hill and Carrboro businesses and community groups are turning the towns pink during the months of September and October to raise funds for UNC Lineberger Comprehensive Cancer Center and its Comprehensive Cancer Support Program.
DALLAS -- An American clinician-scientist and an Israeli researcher whose work has led to more personalized treatments for breast cancer are being honored as this year’s winners of the prestigious Susan G. Komen for the Cure® Brinker Awards for Scientific Distinction in Basic Science and Clinical Research, the highest awards of merit given by the world’s leading breast cancer organization.
WCHL named UNC Lineberger director Shelley Earp, MD, the Village Pride Award Honoree for October 2, 2012. Each weekday the station selects a Hometown Hero who goes “over and above the call of duty,” exemplifying excellent service and dedication to others in the community.
New research from UNC has established the first link between the two most fundamental epigenetic tags -- histone modification and DNA methylation -- in humans.
Chapel Hill, NC – Christophe Guilluy, PhD, Wenjin Liu, PhD and JinZhu Duan, PhD are the first, second, and third place recipients of the Joseph S. Pagano Award for a paper by a postdoctoral fellow published in 2011.
The North Carolina Biotechnology Center recently awarded the Society for Translational Oncology (STO) $5,000 to be used for the organization's annual meeting. This year's meeting "Personalizing Cancer Diagnosis and Treatment 2012" will be held October 20-21 at UNC Lineberger.
Drs. Davis, Lieb and Rathmell, all members of UNC Lineberger, are featured in an article on V's Voice, the blog for The V Foundation for Cancer Research.
Andrew Wang, MD, assistant professor of radiation oncology, has been awarded a $50,000 one-year grant from the Lung Cancer Research Foundation.
A brilliant and beloved scientist has left us too early. Dr. Robert Millikan, Barbara Sorenson Hulka Distinguished Professor of Cancer Epidemiology, died Sunday, October 7. He was 55.
William Valdar, PhD, assistant professor of genetics, has received a 5-year, $1.4 million grant from the National Institute of General Medical Sciences (part of the National Institutes of Health), to develop statistical methods and software to support the design and analysis of experiments that use the Collaborative Cross, a “library” of genetic diversity that scientists believe can help fast-track important discoveries about genetics and disease into new discoveries, tests, and treatments that impact human health.
Election to the IOM is considered one of the highest honors in the fields of health and medicine and recognizes individuals who have demonstrated outstanding professional achievement and commitment to service.
Patient perspective key to adequate evaluation of cancer treatment
Ronald Chen, MD, MPH, assistant professor of Radiation Oncology in the UNC School of Medicine and Bryce Reeve, PhD, associate professor of Health Policy and Management in the Gillings School of Global Public Health have been awarded a four-year, $1,124,226 grant by the National Cancer Institute (NCI). This grant supplements a parent study funded by the Agency for Healthcare Research and Quality (AHRQ) to monitor the recovery, mental well-being and quality of life of prostate cancer patients during the two years following treatment. Both researchers are members of UNC Lineberger Comprehensive Cancer Center.
Close to 150 faculty and postdoctoral fellows gathered at the Kenan Center for the 37th annual UNC Lineberger Postdoc-Faculty Research Day
This year’s speaker was Dr. Brooke McCartney, associate professor in the department of biological sciences at Carnegie Mellon University. She completed her postdoc training in the lab of Dr. Mark Peifer.
Asheville artist Ann Hartline was featured in Family House Diaries in July 2011. Despite new medical challenges over the past year, Ann celebrated five years of living life large with metastatic breast cancer.
Located at the center of campus, the new Genome Sciences Building will help researchers unlock the underlying mechanisms of cancer, in addition to providing space for other groundbreaking research.
Satish Gopal, MD, MPH, assistant professor in the division of hematology/oncology and infectious diseases at the UNC School of Medicine, has received a five-year International Research Scientist Development Award (IRSDA) from the Fogarty International Center of the National Institutes of Health.
There are Top 20 lists for music, books and for articles written about lay health advisors, as reported by the BioMedLib “Who is Publishing in My Domain?” journal.